DETAILS, FICTION AND BETAINE

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The big GTPase dynamin is essential for clathrin-dependent coated-vesicle formation. Dynasore is actually a cell-permeable compact molecule that inhibits the GTPase activity of dynamin1, dynamin2 and Drp1, the mitochondrial dynamin. Dynasore was found within a screen of ~16,000 compounds for inhibitors in the dynamin2 GTPase.The supply of FC in the